Two Types. Confocal microscopy reveals α-synuclein (green) and lipids (red) in three adjacent inclusions (left and right). The white arrows point to Type I inclusions loaded with lipids. Blue ...

Immunotherapy can remove extracellular amyloid plaques from Alzheimer’s brain, but has so far failed to clear intracellular tau tangles. Now, two papers propose a solution: tagging them for ...

Alzheimer’s is a multifaceted disease, particularly in its sporadic, late-onset form. Myriad factors—genetics, environment, ...

On Tuesday September 10, Francisco Lopera died of cancer at his home in Medellin, Colombia. He was 73, and only just beginning to see his life’s work come to fruition. In fact, Lopera still had much ...

But some 80 percent of people with Parkinson's disease have GI problems, such as acid reflux, irritable bowel syndrome, and constipation, which often emerge decades before motor difficulties do. This ...

Physician and Surgeon - Universidad de Antioquia, UA, Antioquia, Colombia. Doctor of Medicine – Magna cum laude - University of Hamburg, Hamburg, HH, Germany. PostDoc – Alzheimer’s Disease ...

I am a co-founder of Treventis Corp. which is a startup biotech dedicated to the design and development of novel small molecule inhibitors of beta-amyloid and tau misfolding and oligomerization.

In Alzheimer’s disease, tau tangles accumulate in the temporal lobe and cortex, but spare other regions such as the cerebellum and brainstem. In a July 31 preprint on bioRxiv, scientists led by Huda ...

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Columbia College in the City of New York Harvard University Graduate School of Arts and Sciences (Neurobiology) Harvard Medical School (MD PhD Program) ...