Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

San Francisco 49ers starting center Jake Brendel has the worst pass-blocking grade in the NFL through two weeks, according to ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

The 49ers' eighth straight loss in Minnesota exposes weaknesses and serves as a reality check for the team's performance.

The San Francisco 49ers and Los Angeles Rams play on Sunday, Sept. 22, at SoFi Stadium in a game on the NFL Week 3 schedule. Which team will win the Week 3 NFL game? Check out these NFL Week 3 ...

Twenty former San Francisco 49ers players and one coaching alum were among the 167 Modern-Era Players nominated for the Pro ...

Sam Darnold shines in Vikings' home debut, leading team to victory over 49ers with impressive passing. Vikings' defense has ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next few weeks. On Monday, 49ers coach Kyle Shanahan told reporters that Samuel will miss "a couple weeks" due to a calf strain ...

The San Francisco 49ers will begin using sustainable aviation fuel (SAF) on chartered United flights for away games. The plan ...

At the time of writing, San Francisco was trailing Minnesota by a score of 20-7 entering the fourth quarter. Before Kittle got carted off to the locker room, he had five catches for 56 yards ...