Jennifer Lee Chan shares the latest injury report for Sunday's San Francisco 49ers vs. Arizona Cardinals game.

The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

College Football Playoff’s final 4 teams, ranked by most likely to win national championship Tiny black holes could be hiding ...

San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to ...

Detroit Lions offense excelled against San Francisco 49ers. Wayne Osmond, founding member of the Osmonds, is dead at 73 ...

San Francisco 49ers quarterback Brock Purdy will miss Sunday's season finale against the Arizona Cardinals due to a right ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...

Detroit Lions offensive tackle Penei Sewell has been selected to his third consecutive NFC Pro Bowl roster, but the former Oregon Ducks unanimous All-American s ...

The Detroit Lions and Minnesota Vikings will wrap up the NFL's regular season on Sunday night with a lot at stake.

Lenoir appears to have sustained a shoulder injury in the 49ers' Week 17 loss to the Lions, despite playing 100 percent of the team's defensive snaps and recording nine total tackles. The Oregon ...

The San Francisco 49ers are preparing for their Week 18 contest against the Arizona Cardinals on Sunday at State Farm Stadium in Glendale, Arizona. Both ...

Gibbs has taken the workhorse role in the first two games without Montgomery and run with the opportunity. He has back-to-back games with 100-plus rushing yards, and has continued to be a receiving ...